JOURNAL OF MEDICAL BIOCHEMISTRY / 2014-1 „JOURNAL OF MEDICAL BIOCHEMISTRY“Official Journal of the Serbian Society of Medical Biochemists Volume: 33-1 EDITORIALNada Majkić-Singh, Zorica Šumarac, Anđelo BeletićINTEGRATIVE ALGORITHMS IN PATIENT FOCUSED LABORATORY MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . 1REVIEW ARTICLEIvana Novaković, Nela Maksimović, Aleksandra Pavlović, Milena Žarković,Branislav Rovčanin, Duško Mirković, Tatjana Pekmezović, Dragana CvetkovićINTRODUCTION TO MOLECULAR GENETIC DIAGNOSTICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3Sonja Pavlović, Branka Zukić, Maja Stojiljković PetrovićMOLECULAR GENETIC MARKERS AS A BASIS FOR PERSONALIZED MEDICINE . . . . . . . . . . . . . . . . . . . . . 8Valentina Đorđević, Iva Pruner, Dragica RadojkovićMOLECULAR BASIS OF THROMBOPHILIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22Sandra MargetićLABORATORY INVESTIGATION OF THROMBOPHILIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28Gorana MitićAN INTEGRATIVE APPROACH TO THE PATIENT WITH THROMBOPHILIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . 47Elizabeta TopićTHE ROLE OF PHARMACOGENETICS IN THE TREATMENT OF DIABETES MELLITUS . . . . . . . . . . . . . . . .58Sanja Stanković, Milika Ašanin, Nada Majkić-SinghTHE PHARMACOGENETICS OF CARDIOVASCULAR DRUGS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71Ksenija Fumić, Karmen Bilić, Dunja RogićINTEGRATIVE ALGORITHMS IN THE DIAGNOSTICS OF LYSOSOMAL STORAGE DISEASES . . . . . . . . . . .82Anđelo Beletić, Aleksandra Dudvarski-Ilić, Branislava Milenković,Ljudmila Nagorni-Obradović, Mila Ljujić, Valentina Đorđević, Dragica Radojković, Nada Majkić-SinghALPHA-1-ANTITRYPSIN DEFICIENCY – MOLECULAR BASIS, CLINICALPRESENTATION, THERAPEUTIC OPTIONS AND AN INTEGRATIVE APPROACH IN DIAGNOSTICS . . . . 88Maja Stojiljković-Petrović, Kristel Klaassen, Sonja PavlovićMOLECULAR CHARACTERISTICS, PHENOTYPIC DIVERSITY AND GENOTYPE-ESTIMATEDTHERAPEUTIC RESPONSIVENESS OF SERBIAN PATIENTS WITH PHENYLKETONURIA . . . . . . . . . . . . 97TECHNICAL REPORTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . .115NEWS FROM THE SOCIETY OF MEDICAL BIOCHEMISTS OF SERBIA . . . . . . . . . . . . . . . . . . . . . . . . . . . . .117INSTRUCTIONS FOR AUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123Volume: 33 Belgrade, January – March 2014 Issue: 1JMB 2014; 33 (1): 1–134 © 2014 by SMBS, Belgrade